15 Best Business Hotels in Durham, NC (2026)

Business Hotels in Durham, NC: Rates Starting at $111 per Night

Washington Duke Inn & Golf Club
Hotel
3001 Cameron Boulevard, Durham, NC 27705, USA
• View on map
  • Private Pool
    Private Pool
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Fireplace/Heating
    Fireplace/Heating
9 Baths344.45 ft²
9.3

Exceptional

90 reviews

$278
Average price / night
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21c Museum Hotel Durham
Hotel
111 North Corcoran Street, Durham, NC 27701, USA
• View on map
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
  • Breakfast
    Breakfast
  • Pet Friendly
    Pet Friendly
15 Baths450.65 ft²
7.8

Exceptional

359 reviews

$168
Average price / night
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The Durham Hotel
Hotel
315 East Chapel Hill Street, Durham, NC 27701, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
  • Kitchen
    Kitchen
  • Parking
    Parking
7 Baths316.77 ft²
6.9

Exceptional

46 reviews

$236
Average price / night
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Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park
Hotel
151 Tatum Drive, Durham, NC 27703, USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Ocean View
    Ocean View
  • Balcony/Terrace
    Balcony/Terrace
  • Highly Rated
    Highly Rated
  • Free Cancellation
3 Baths340.86 ft²
9.1

Exceptional

263 reviews

$262
Average price / night
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Hyatt Place Durham Southpoint
Hotel
7840 NC 751 Hwy, Durham, NC 27713 , USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Ocean View
    Ocean View
8 Baths485.72 ft²
8.8

Exceptional

567 reviews

$136
Average price / night
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Aloft by Marriott Durham Downtown
Hotel
345 Blackwell Street, Durham, 27701, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Balcony/Terrace
    Balcony/Terrace
  • View
    View
7 Baths367.51 ft²
8.9

Exceptional

105 reviews

$324
Average price / night
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Marriott Raleigh Durham Research Triangle Park
Hotel
4700 Guardian Drive, Durham, NC 27703, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
  • Kitchen
    Kitchen
  • Parking
    Parking
10 Baths322.92 ft²
8.1

Exceptional

63 reviews

$200
Average price / night
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Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle Park
Hotel
4700 Emperor Boulevard, Durham, NC 27703, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Balcony/Terrace
    Balcony/Terrace
  • Breakfast
    Breakfast
9 Baths367.17 ft²
8.1

Exceptional

110 reviews

$275
Average price / night
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Durham Marriott City Center
Hotel
201 Foster Street, Durham, NC 27701, USA
• View on map
  • Balcony/Terrace
    Balcony/Terrace
  • Parking
    Parking
  • Air Conditioner
    Air Conditioner
  • Internet
    Internet
9 Baths343.25 ft²
8.1

Exceptional

111 reviews

$229
Average price / night
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DoubleTree by Hilton Raleigh Durham Airport at Research Triangle Park
Hotel
4810 Page Creek Lane, Durham, NC 27703, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Balcony/Terrace
    Balcony/Terrace
  • Breakfast
    Breakfast
12 Baths352.52 ft²
8.4

Exceptional

232 reviews

$129
Average price / night
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JB Duke Hotel
Hotel
230 Science Drive, Durham, NC 27708, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
  • Breakfast
    Breakfast
  • Pet Friendly
    Pet Friendly
7 Baths475.15 ft²
9.1

Exceptional

89 reviews

$338
Average price / night
Check Availability
Homewood Suites Durham-Chapel Hill I-40
Hotel
3600 Mount Moriah Road, Durham, NC 27707, USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Ocean View
    Ocean View
1 Baths5166.67 ft²
8.2

Exceptional

96 reviews

$128
Average price / night
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SpringHill Suites Durham Chapel Hill
Hotel
5310 McFarland Drive, Durham, NC 27707, USA
• View on map
  • Private Pool
    Private Pool
  • Pool
    Pool
  • Breakfast
    Breakfast
  • Parking
    Parking
6 Baths290.63 ft²
8.7

Exceptional

128 reviews

$139
Average price / night
Check Availability
DoubleTree Suites by Hilton Raleigh-Durham
Hotel
2515 Meridian Parkway, Durham, NC 27713-5221, USA
• View on map
  • Private Pool
    Private Pool
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Balcony/Terrace
    Balcony/Terrace
1 Baths563.64 ft²
8.7

Exceptional

535 reviews

$111
Average price / night
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Residence Inn by Marriott Durham Duke University Medical Center Area
Hotel
1108 West Main Street, Durham, NC 27701, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
  • Breakfast
    Breakfast
  • Pet Friendly
    Pet Friendly
13 Baths470.3 ft²
8.4

Exceptional

50 reviews

$213
Average price / night
Check Availability

Compare the 15 Best Business Hotels in Durham, NC (2026) – Addresses, Prices, Stars, Rating, and Review Count

Hotel Name Address Price ($)Star Rating Review Count Book
Washington Duke Inn & Golf Club3001 Cameron Boulevard, Durham, NC 27705, USA27849.390
21c Museum Hotel Durham111 North Corcoran Street, Durham, NC 27701, USA16857.8359
The Durham Hotel315 East Chapel Hill Street, Durham, NC 27701, USA23646.946
Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park151 Tatum Drive, Durham, NC 27703, USA26239.1263
Hyatt Place Durham Southpoint7840 NC 751 Hwy, Durham, NC 27713 , USA13638.8567
Aloft by Marriott Durham Downtown345 Blackwell Street, Durham, 27701, USA32448.9105
Marriott Raleigh Durham Research Triangle Park4700 Guardian Drive, Durham, NC 27703, USA20038.163
Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle Park4700 Emperor Boulevard, Durham, NC 27703, USA27538.1110
Durham Marriott City Center201 Foster Street, Durham, NC 27701, USA22948.1111
DoubleTree by Hilton Raleigh Durham Airport at Research Triangle Park4810 Page Creek Lane, Durham, NC 27703, USA12948.4232
JB Duke Hotel230 Science Drive, Durham, NC 27708, USA33849.189
Homewood Suites Durham-Chapel Hill I-403600 Mount Moriah Road, Durham, NC 27707, USA12838.296
SpringHill Suites Durham Chapel Hill5310 McFarland Drive, Durham, NC 27707, USA13938.7128
DoubleTree Suites by Hilton Raleigh-Durham2515 Meridian Parkway, Durham, NC 27713-5221, USA11138.7535
Residence Inn by Marriott Durham Duke University Medical Center Area1108 West Main Street, Durham, NC 27701, USA21338.450

Note: The prices for each 15 Best Business Hotels in Durham, NC (2026) do vary. This can be because of the number of people you are booking for, how far in advance you book and the season. The prices above are only meant as a rough estimate for comparison purposes. Click the buttons above (or click here>) to get the latest prices.

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