12 Best Business Hotels in Greenville, SC (2026)

Business Hotels in Greenville, SC: Rates Starting from $108 per Night

The Westin Poinsett, Greenville
Hotel
120 South Main Street, Downtown Greenville, Greenville, SC 29601-2711, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Pet Friendly
    Pet Friendly
  • Kitchen
    Kitchen
  • Parking
    Parking
  • Highly Rated
    Highly Rated
  • Free Cancellation
5 Baths391.81 ft²
9.1

Exceptional

172 reviews

$399
Average price / night
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Greenville Marriott
Hotel
One Parkway East, Greenville, SC 29615, USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Ocean View
    Ocean View
7 Baths236.81 ft²
7.6

Exceptional

114 reviews

$169
Average price / night
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Drury Inn & Suites Greenville
Hotel
10 Carolina Point Parkway, Greenville, SC 29607-5764, USA
• View on map
  • Hot Tub
    Hot Tub
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Pet Friendly
    Pet Friendly
  • Highly Rated
    Highly Rated
  • Family Friendly
18 Baths340.86 ft²
9.1

Exceptional

917 reviews

$190
Average price / night
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Embassy Suites by Hilton Greenville Downtown Riverplace
Hotel
250 Riverplace , Downtown Greenville, Greenville, SC 29601, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Parking
    Parking
  • Air Conditioner
    Air Conditioner
1 Baths500.11 ft²
8.8

Exceptional

298 reviews

$460
Average price / night
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Hilton Garden Inn Greenville
Hotel
108 Carolina Point Parkway, Greenville, SC 29605, USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Ocean View
    Ocean View
1 Baths322.92 ft²
8.5

Exceptional

194 reviews

$228
Average price / night
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Hampton Inn & Suites Greenville-Downtown-Riverplace
Hotel
171 RiverPlace, Downtown Greenville, Greenville, SC 29601, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
  • View
    View
  • Breakfast
    Breakfast
  • Highly Rated
    Highly Rated
  • Family Friendly
1 Baths269.1 ft²
9

Exceptional

425 reviews

$174
Average price / night
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Staybridge Suites Greenville I-85 Woodruff Road by IHG
Hotel
31 Market Point Drive, Greenville, SC 29607, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Balcony/Terrace
    Balcony/Terrace
  • Pet Friendly
    Pet Friendly
  • Highly Rated
    Highly Rated
  • Family Friendly
9 Baths525.04 ft²
9.2

Exceptional

98 reviews

$168
Average price / night
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Residence Inn Greenville-Spartanburg Airport
Hotel
120 Milestone Way, Greenville, SC 29615, USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Ocean View
    Ocean View
6 Baths457.46 ft²
8.5

Exceptional

52 reviews

$186
Average price / night
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Crowne Plaza Greenville by IHG
Hotel
851 Congaree Road, Greenville, SC 29607, USA
• View on map
  • Private Pool
    Private Pool
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
8 Baths398.26 ft²
8

Exceptional

345 reviews

$108
Average price / night
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Courtyard Greenville Haywood Mall
Hotel
70 Orchard Park Drive, Greenville, SC 29615, USA
• View on map
  • Pool
    Pool
  • Pet Friendly
    Pet Friendly
  • Parking
    Parking
  • Air Conditioner
    Air Conditioner
  • Price Dropped
    Price Dropped
  • Family Friendly
6 Baths261.65 ft²
8.9

Exceptional

152 reviews

$184
Average price / night
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Hampton Inn Greenville/Woodruff Road
Hotel
15 Park Woodruff Drive, Greenville, SC 29607, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Breakfast
    Breakfast
  • Pet Friendly
    Pet Friendly
1 Baths304.47 ft²
8.4

Exceptional

226 reviews

$144
Average price / night
Check Availability
Holiday Inn Greenville by IHG
Hotel
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Balcony/Terrace
    Balcony/Terrace
  • Breakfast
    Breakfast
1 Baths
8.2

Exceptional

341 reviews

$183
Average price / night
Check Availability

Compare the 12 Best Business Hotels in Greenville, SC (2026) – Addresses, Prices, Stars, Rating, and Review Count

Hotel Name Address Price ($)Star Rating Review Count Book
The Westin Poinsett, Greenville120 South Main Street, Downtown Greenville, Greenville, SC 29601-2711, USA39949.1172
Greenville MarriottOne Parkway East, Greenville, SC 29615, USA16947.6114
Drury Inn & Suites Greenville10 Carolina Point Parkway, Greenville, SC 29607-5764, USA19039.1917
Embassy Suites by Hilton Greenville Downtown Riverplace250 Riverplace , Downtown Greenville, Greenville, SC 29601, USA46048.8298
Hilton Garden Inn Greenville108 Carolina Point Parkway, Greenville, SC 29605, USA22838.5194
Hampton Inn & Suites Greenville-Downtown-Riverplace171 RiverPlace, Downtown Greenville, Greenville, SC 29601, USA17439425
Staybridge Suites Greenville I-85 Woodruff Road by IHG31 Market Point Drive, Greenville, SC 29607, USA16839.298
Residence Inn Greenville-Spartanburg Airport120 Milestone Way, Greenville, SC 29615, USA18638.552
Crowne Plaza Greenville by IHG851 Congaree Road, Greenville, SC 29607, USA10848345
Courtyard Greenville Haywood Mall70 Orchard Park Drive, Greenville, SC 29615, USA18438.9152
Hampton Inn Greenville/Woodruff Road15 Park Woodruff Drive, Greenville, SC 29607, USA14438.4226

Note: The prices for each 12 Best Business Hotels in Greenville, SC (2026) do vary. This can be because of the number of people you are booking for, how far in advance you book and the season. The prices above are only meant as a rough estimate for comparison purposes. Click the buttons above (or click here>) to get the latest prices.

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