14 Best Business Hotels in Key West, FL (2026)

Business Hotels in Key West, FL: Rates Starting at $184 per Night

The Reach Key West, Curio Collection by Hilton
Resort
1435 Simonton Street, Downtown Key West, Key West, FL 33040, USA
• View on map
  • Private Beach
    Private Beach
  • Oceanfront
    Oceanfront
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
1 Baths355.21 ft²
7.4

Exceptional

236 reviews

$419
Average price / night
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Opal Key Resort & Marina
Resort
245 Front Street, Downtown Key West, Key West, 33040, USA
• View on map
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
27 Baths631.16 ft²
8.6

Exceptional

1135 reviews

$472
Average price / night
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Parrot Key Hotel & Villas
Resort
2801 North Roosevelt Boulevard, Key West, FL 33040, USA
• View on map
  • Oceanfront
    Oceanfront
  • Pool
    Pool
  • Ocean View
    Ocean View
  • Balcony/Terrace
    Balcony/Terrace
31 Baths786.9 ft²
8.3

Exceptional

3257 reviews

$219
Average price / night
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Pier House Resort & Spa
Resort
One Duval Street, Downtown Key West, Key West, FL 33040, USA
• View on map
  • Private Beach
    Private Beach
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
9 Baths1126.02 ft²
8.4

Exceptional

602 reviews

$534
Average price / night
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Casa Marina Key West, Curio Collection by Hilton
Resort
• View on map
  • Private Beach
    Private Beach
  • Oceanfront
    Oceanfront
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
1 Baths486.43 ft²
7.9

Exceptional

263 reviews

$512
Average price / night
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Margaritaville Beach House Key West
Hotel
2001 South Roosevelt Boulevard, Key West, FL 33040, USA
• View on map
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
10 Baths464.64 ft²
8.1

Exceptional

717 reviews

$300
Average price / night
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Amsterdam's Curry Mansion Inn
Bed & Breakfast
• View on map
  • Pool
    Pool
  • Balcony/Terrace
    Balcony/Terrace
  • Breakfast
    Breakfast
  • Pet Friendly
    Pet Friendly
6 Baths361.67 ft²
8.8

Exceptional

139 reviews

$563
Average price / night
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Courtyard by Marriott Key West Waterfront
Hotel
3031-41 North Roosevelt Boulevard, Key West, FL 33040, USA
• View on map
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
8 Baths287.93 ft²
8.3

Exceptional

369 reviews

$505
Average price / night
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Fairfield by Marriott Inn & Suites Key West at The Keys Collection
Hotel
3852 North Roosevelt Boulevard, Key West, FL 33040, USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Ocean View
    Ocean View
  • Price Dropped
    Price Dropped
  • Free Cancellation
18 Baths317.54 ft²
8.3

Exceptional

2284 reviews

$186
Average price / night
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Hilton Garden Inn Key West/The Keys Collection
Hotel
3850 North Roosevelt Boulevard, Key West, FL 33040, USA
• View on map
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Pool
    Pool
  • Ocean View
    Ocean View
1 Baths285.24 ft²
7.6

Exceptional

1014 reviews

$184
Average price / night
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DoubleTree by Hilton Grand Key Resort
Resort
3990 South Roosevelt Boulevard, Key West, FL 33040, USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Ocean View
    Ocean View
3 Baths315.74 ft²
8

Exceptional

600 reviews

$196
Average price / night
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The Perry Hotel & Marina Key West
Resort
7001 Shrimp Rd, Key West, 33040, USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Ocean View
    Ocean View
3 Baths394.42 ft²
8.9

Exceptional

450 reviews

$883
Average price / night
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The Grand Guesthouse
Bed & Breakfast
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Ocean View
    Ocean View
  • Balcony/Terrace
    Balcony/Terrace
5 Baths232.5 ft²
8.5

Exceptional

806 reviews

$437
Average price / night
Check Availability
The Key West Hotel
Hotel
325 Duval Street, Downtown Key West, Key West, FL 33040, USA
• View on map
  • Oceanfront
    Oceanfront
  • Pool
    Pool
  • Ocean View
    Ocean View
  • View
    View
6 Baths400.42 ft²
7

Exceptional

12 reviews

$421
Average price / night
Check Availability

Compare the 14 Best Business Hotels in Key West, FL (2026) – Addresses, Prices, Stars, Rating, and Review Count

Hotel Name Address Price ($)Star Rating Review Count Book
The Reach Key West, Curio Collection by Hilton1435 Simonton Street, Downtown Key West, Key West, FL 33040, USA41947.4236
Opal Key Resort & Marina245 Front Street, Downtown Key West, Key West, 33040, USA47248.61135
Parrot Key Hotel & Villas2801 North Roosevelt Boulevard, Key West, FL 33040, USA21948.33257
Pier House Resort & SpaOne Duval Street, Downtown Key West, Key West, FL 33040, USA53448.4602
Margaritaville Beach House Key West2001 South Roosevelt Boulevard, Key West, FL 33040, USA30038.1717
Courtyard by Marriott Key West Waterfront3031-41 North Roosevelt Boulevard, Key West, FL 33040, USA50538.3369
Fairfield by Marriott Inn & Suites Key West at The Keys Collection3852 North Roosevelt Boulevard, Key West, FL 33040, USA18638.32284
Hilton Garden Inn Key West/The Keys Collection3850 North Roosevelt Boulevard, Key West, FL 33040, USA18437.61014
DoubleTree by Hilton Grand Key Resort3990 South Roosevelt Boulevard, Key West, FL 33040, USA19648600
The Perry Hotel & Marina Key West7001 Shrimp Rd, Key West, 33040, USA88348.9450
The Key West Hotel325 Duval Street, Downtown Key West, Key West, FL 33040, USA4213712

Note: The prices for each 14 Best Business Hotels in Key West, FL (2026) do vary. This can be because of the number of people you are booking for, how far in advance you book and the season. The prices above are only meant as a rough estimate for comparison purposes. Click the buttons above (or click here>) to get the latest prices.

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