12 Best Business Hotels in South Carolina (2026)

Business Hotels in South Carolina: Rates Starting at $264 per Night

Montage Palmetto Bluff
Hotel
477 Mount Pelia Road, Bluffton, SC 29910, USA
• View on map
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
47 Baths1094.95 ft²
8.4

Exceptional

34 reviews

$651
Average price / night
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Harbourview Inn
Hotel
2 Vendue Range, Historic District, Charleston, SC 29401, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
  • Breakfast
    Breakfast
  • Parking
    Parking
11 Baths386.52 ft²
9.3

Exceptional

672 reviews

$462
Average price / night
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Omni Hilton Head Oceanfront Resort
Hotel
23 Ocean Lane, Hilton Head Island, SC 29928, USA
• View on map
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
  • Top 20% in Palmetto Dunes
    Top 20% in Palmetto Dunes
  • Ocean View
17 Baths609.74 ft²
8.5

Exceptional

475 reviews

$453
Average price / night
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The Westin Hilton Head Island Resort & Spa
Resort
2 Grasslawn Avenue, Hilton Head Island, SC 29928, USA
• View on map
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
14 Baths564.34 ft²
8.4

Exceptional

403 reviews

$396
Average price / night
Check Availability
The Willcox
Hotel
100 Colleton Avenue Southwest, Aiken, SC 29801, USA
• View on map
  • Oceanfront
    Oceanfront
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
7 Baths464.39 ft²
9.6

Exceptional

40 reviews

$286
Average price / night
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The Westin Poinsett, Greenville
Hotel
120 South Main Street, Downtown Greenville, Greenville, SC 29601-2711, USA
• View on map
  • Fireplace/Heating
    Fireplace/Heating
  • Pet Friendly
    Pet Friendly
  • Kitchen
    Kitchen
  • Parking
    Parking
  • Highly Rated
    Highly Rated
  • Free Cancellation
5 Baths391.81 ft²
9.1

Exceptional

172 reviews

$399
Average price / night
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Marina Inn at Grande Dunes
Resort
8121 Amalfi Place, Myrtle Beach, SC 29572, USA
• View on map
  • Private Pool
    Private Pool
  • Private Beach
    Private Beach
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
6 Baths2555.35 ft²
9.2

Exceptional

497 reviews

$508
Average price / night
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The Lindy Renaissance Charleston Hotel
Hotel
68 Wentworth Street, Historic District, Charleston, SC 29401, USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Ocean View
    Ocean View
4 Baths314.85 ft²
8.9

Exceptional

35 reviews

$264
Average price / night
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Market Pavilion Hotel
Hotel
225 East Bay Street, Historic District, Charleston, SC 29401, USA
• View on map
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Ocean View
    Ocean View
  • Highly Rated
    Highly Rated
  • Ocean View
5 Baths406.88 ft²
9

Exceptional

667 reviews

$411
Average price / night
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Inn and Club at Harbour Town
Resort
7 Lighthouse Lane, Hilton Head Island, SC 29928, USA
• View on map
  • Hot Tub
    Hot Tub
  • Pool
    Pool
  • Balcony/Terrace
    Balcony/Terrace
  • Breakfast
    Breakfast
8 Baths484.38 ft²
9.3

Exceptional

92 reviews

$432
Average price / night
Check Availability
Harborside at Charleston Harbor Resort and Marina
Resort
• View on map
  • Private Beach
    Private Beach
  • Hot Tub
    Hot Tub
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
1 Baths301.39 ft²
8

Exceptional

286 reviews

$425
Average price / night
Check Availability
Hotel Bennett Charleston
Hotel
404 King Street, Historic District, Charleston, SC 29403, USA
• View on map
  • Oceanfront
    Oceanfront
  • Spa
    Spa
  • Pool
    Pool
  • Ocean View
    Ocean View
  • Highly Rated
    Highly Rated
  • Ocean View
12 Baths449.39 ft²
9.5

Exceptional

124 reviews

$493
Average price / night
Check Availability

Compare the 12 Best Business Hotels in South Carolina (2026) – Addresses, Prices, Stars, Rating, and Review Count

Hotel Name Address Price ($)Star Rating Review Count Book
Montage Palmetto Bluff477 Mount Pelia Road, Bluffton, SC 29910, USA65158.434
Harbourview Inn2 Vendue Range, Historic District, Charleston, SC 29401, USA46249.3672
Omni Hilton Head Oceanfront Resort23 Ocean Lane, Hilton Head Island, SC 29928, USA45348.5475
The Westin Hilton Head Island Resort & Spa2 Grasslawn Avenue, Hilton Head Island, SC 29928, USA39648.4403
The Willcox100 Colleton Avenue Southwest, Aiken, SC 29801, USA28649.640
The Westin Poinsett, Greenville120 South Main Street, Downtown Greenville, Greenville, SC 29601-2711, USA39949.1172
Marina Inn at Grande Dunes8121 Amalfi Place, Myrtle Beach, SC 29572, USA50849.2497
The Lindy Renaissance Charleston Hotel68 Wentworth Street, Historic District, Charleston, SC 29401, USA26448.935
Market Pavilion Hotel225 East Bay Street, Historic District, Charleston, SC 29401, USA41149667
Inn and Club at Harbour Town7 Lighthouse Lane, Hilton Head Island, SC 29928, USA43259.392
Hotel Bennett Charleston404 King Street, Historic District, Charleston, SC 29403, USA49359.5124

Note: The prices for each 12 Best Business Hotels in South Carolina (2026) do vary. This can be because of the number of people you are booking for, how far in advance you book and the season. The prices above are only meant as a rough estimate for comparison purposes. Click the buttons above (or click here>) to get the latest prices.

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