8 Best Hotels with Spa in Missouri (2026)

Hotels with Spa in Missouri: Enjoy Luxury Starting at $110 per Night

Camden on the Lake Resort
Resort
2359 Bittersweet Road, Lake Ozark, MO 65049, USA
• View on map
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
5 Baths540.35 ft²
8.9

Exceptional

304 reviews

$261
Average price / night
Check Availability
21c Museum Hotel St Louis
Hotel
1528 Locust street, Downtown St. Louis, Saint Louis, 63103, USA
• View on map
  • Private Pool
    Private Pool
  • Hot Tub
    Hot Tub
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
10 Baths500.52 ft²
8.5

Exceptional

1040 reviews

$185
Average price / night
Check Availability
The Raphael Hotel, Autograph Collection
Hotel
325 Ward Parkway, Kansas City, MO 64112, USA
• View on map
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
  • Breakfast
    Breakfast
9 Baths429.36 ft²
8.8

Exceptional

101 reviews

$899
Average price / night
Check Availability
The Ritz-Carlton, St. Louis
Hotel
100 Carondelet Plaza, Clayton, MO 63105, USA
• View on map
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
  • Breakfast
    Breakfast
  • Pet Friendly
    Pet Friendly
10 Baths632.92 ft²
8.7

Exceptional

32 reviews

$609
Average price / night
Check Availability
Lodge of Four Seasons Golf Resort, Marina & Spa
Resort
• View on map
  • Private Pool
    Private Pool
  • Private Beach
    Private Beach
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
7 Baths428.76 ft²
7

Exceptional

527 reviews

$1365
Average price / night
Check Availability
Oasis Hotel and Conv Center, an Ascend Collection Hotel
Hotel
2546 N Glenstone , Springfield, 65803, USA
• View on map
  • Pool
    Pool
  • Pet Friendly
    Pet Friendly
  • Parking
    Parking
  • Air Conditioner
    Air Conditioner
10 Baths369.2 ft²
8.8

Exceptional

535 reviews

$110
Average price / night
Check Availability
Four Seasons St. Louis
Hotel
999 North 2nd Street, Downtown St. Louis, Saint Louis, MO 63102, USA
• View on map
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
  • Highly Rated
    Highly Rated
  • Free Cancellation
18 Baths798.32 ft²
9.2

Exceptional

92 reviews

$667
Average price / night
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Chateau on the Lake Resort Spa and Convention Center
Resort
415 North State Highway 265, Branson, MO 65616, USA
• View on map
  • Private Pool
    Private Pool
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
11 Baths508.84 ft²
8

Exceptional

753 reviews

$305
Average price / night
Check Availability

Compare the 8 Best Hotels with Spa in Missouri (2026) – Addresses, Prices, Stars, Rating, and Review Count

Hotel Name Address Price ($)Star Rating Review Count Book
Camden on the Lake Resort2359 Bittersweet Road, Lake Ozark, MO 65049, USA26148.9304
21c Museum Hotel St Louis1528 Locust street, Downtown St. Louis, Saint Louis, 63103, USA18548.51040
The Raphael Hotel, Autograph Collection325 Ward Parkway, Kansas City, MO 64112, USA89948.8101
The Ritz-Carlton, St. Louis100 Carondelet Plaza, Clayton, MO 63105, USA60958.732
Oasis Hotel and Conv Center, an Ascend Collection Hotel2546 N Glenstone , Springfield, 65803, USA11048.8535
Four Seasons St. Louis999 North 2nd Street, Downtown St. Louis, Saint Louis, MO 63102, USA66759.292
Chateau on the Lake Resort Spa and Convention Center415 North State Highway 265, Branson, MO 65616, USA30548753

Note: The prices for each 8 Best Hotels with Spa in Missouri (2026) do vary. This can be because of the number of people you are booking for, how far in advance you book and the season. The prices above are only meant as a rough estimate for comparison purposes. Click the buttons above (or click here>) to get the latest prices.

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