The KeysLuxury Hotels with Spa

List Of Best Luxury Hotels with Spa The Keys

We have created a list with the best hotels with spa in The Keys, USA. Hope you enjoy it. We think it might be the best of its kind around

luxury hotels in The Keys
Cheeca Lodge & Spa
Resort
81801 Overseas Highway Mile Marker 82, Islamorada, FL 33036, USA

Welcome to Cheeca Lodge & Spa, a beautiful resort nestled in Islamorada, Florida, surrounded by 27 acres of stunning gardens and offering a private waterfront for your enjoyment. Whether you're looking to relax or have an adventure, our resort has something for everyone. You can play a round of golf on our charming 9-hole par 3 course, or treat yourself to some well-deserved pampering at our on-site spa. With a variety of accommodations available, we strive to create a comfortable and inviting atmosphere for all our guests. We believe that every visitor deserves a special experience, and our friendly staff is here to help you make the most of your stay. Come discover the beauty and tranquility of Cheeca Lodge & Spa, where you can unwind and connect with nature in a welcoming environment.

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Luxury Amenities:

  1. Enjoy the serenity of your own private beach, with soft sands and endless ocean views.
  2. Wake up to breathtaking ocean views, a stunning start to every morning.
  3. Stay right on the oceanfront and let the sound of waves become your personal soundtrack.
  4. Enjoy convenient transportation with our exclusive shuttle services for seamless travel.
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luxury hotels in The Keys
Playa Largo Resort & Spa, Autograph Collection
Resort
97450 Overseas Highway, Key Largo, FL 33037, USA

Welcome to Playa Largo Resort & Spa, a beautiful destination where you can unwind in one of our 155 luxurious rooms, all filled with natural light and stunning views of Florida Bay. Enjoy breathtaking sunsets that paint the sky in vibrant colors every evening. We are proud to be the first new resort built in the Florida Keys in over 23 years, bringing fresh energy and modern comforts to this stunning area. Whether you're here for a family vacation, a romantic getaway, or a solo retreat, our goal is to create a welcoming and memorable experience for everyone who visits us.

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Luxury Amenities:

  1. Enjoy the serenity of your own private beach, with soft sands and endless ocean views.
  2. Wake up to breathtaking ocean views, a stunning start to every morning.
  3. Stay right on the oceanfront and let the sound of waves become your personal soundtrack.
  4. Stay productive with top-notch business services available at your fingertips.
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luxury hotels in The Keys
Isla Bella Beach Resort & Spa - Florida Keys
Resort
1 Knights Key Boulevard MM47, Marathon, FL 33050, USA

Welcome to Isla Bella Beach Resort, a beautiful getaway located in Marathon. Here, you can enjoy a stunning private beach that’s perfect for relaxation and fun in the sun. We’re conveniently close to exciting attractions like Conch-Air Florida Keys Scenic Flights, just 7 km away, and the Florida Keys Aquarium Encounters, which is only 10 km from our resort. With so much to see and do nearby, you’ll have plenty of opportunities to explore and create lasting memories with your loved ones. We can’t wait to welcome you!

Show more

Luxury Amenities:

  1. Enjoy the serenity of your own private beach, with soft sands and endless ocean views.
  2. Wake up to breathtaking ocean views, a stunning start to every morning.
  3. Stay right on the oceanfront and let the sound of waves become your personal soundtrack.
  4. Enjoy convenient transportation with our exclusive shuttle services for seamless travel.
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luxury hotels in The Keys
Santa Maria Suites Resort
Resort
1401 Simonton Street, Downtown Key West, Key West, FL 33040, USA

Just a short stroll from the beautiful Atlantic Ocean and vibrant Duval Street, our Key West hotel offers stunning all-suite accommodations designed for your comfort. We aim to create a welcoming atmosphere where everyone can relax and enjoy the unique charm of Key West, FL. Whether you're here for a romantic getaway, a family vacation, or a friends' retreat, we want to make sure you have an unforgettable experience that meets your needs. Come and discover the beauty of Key West with us!

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Luxury Amenities:

  1. Wake up to breathtaking ocean views, a stunning start to every morning.
  2. Stay right on the oceanfront and let the sound of waves become your personal soundtrack.
  3. Keep active with a range of sports and activities designed for adventure and fitness.
  4. Rejuvenate at the state-of-the-art wellness facilities designed for your complete relaxation.
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luxury hotels in The Keys
The Gardens Hotel
Hotel
526 Angela Street, Downtown Key West, Key West, FL 33040, USA

Welcome to our adult-only hotel in the beautiful Key West, Florida! Here, you can unwind and enjoy two inviting outdoor pools. We’re conveniently located just a minute’s walk from lively Duval Street, where you can explore shops, restaurants, and nightlife. If you’re interested in nature, the Key West Butterfly and Nature Conservatory is only a quick 3-minute drive away. We look forward to helping you create wonderful memories during your stay!

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Luxury Amenities:

  1. Wake up to breathtaking ocean views, a stunning start to every morning.
  2. Stay right on the oceanfront and let the sound of waves become your personal soundtrack.
  3. Enjoy convenient transportation with our exclusive shuttle services for seamless travel.
  4. Stay productive with top-notch business services available at your fingertips.
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luxury hotels in The Keys
Ocean Key Resort & Spa, a Noble House Resort
Resort
Zero Duval, Downtown Key West, Key West, FL 33040, USA

Experience the beauty of the Gulf of Mexico at our inviting Key West resort and spa. Enjoy relaxing moments by our outdoor pool, where you can take in stunning views of the water. We want to make your stay comfortable, so we offer free WiFi for all our guests. If you’re looking to unwind, visit SpaTerre on-site, where our skilled therapists offer a variety of massage treatments designed just for you. Your comfort and enjoyment are our top priorities!

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Luxury Amenities:

  1. Wake up to breathtaking ocean views, a stunning start to every morning.
  2. Stay right on the oceanfront and let the sound of waves become your personal soundtrack.
  3. Stay productive with top-notch business services available at your fingertips.
  4. Keep active with a range of sports and activities designed for adventure and fitness.
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luxury hotels in The Keys
JW Marriott Marco Island Beach Resort
Resort
400 South Collier Boulevard, Marco Island, FL 34145, USA

Welcome to our beautiful beachfront resort on Marco Island, Florida! Here, you can relax by one of our three outdoor pools or enjoy a round of golf at one of our two private 18-hole courses. We offer a variety of dining options with ten different restaurants to suit all tastes. Plus, there are plenty of activities available for everyone, including volleyball and more. Whether you're looking to unwind or stay active, we have something for everyone to enjoy during your stay!

Show more

Luxury Amenities:

  1. Enjoy the serenity of your own private beach, with soft sands and endless ocean views.
  2. Wake up to breathtaking ocean views, a stunning start to every morning.
  3. Stay right on the oceanfront and let the sound of waves become your personal soundtrack.
  4. Enjoy convenient transportation with our exclusive shuttle services for seamless travel.
Show more
luxury hotels in The Keys
Naples Bay Resort and Marina
Resort
1500 5th Avenue South, Naples, FL 34102, USA

Welcome to Naples Bay Resort and Marina, a place where you can relax and enjoy the beautiful surroundings. Our resort offers a lovely marina and a spacious 5,000-square-foot outdoor pool—perfect for soaking up the sun or enjoying a refreshing swim. Each of our comfortable rooms is equipped with free WiFi, so you can stay connected during your visit. Plus, we’re conveniently located just under a mile from the scenic Naples Pier, where you can take in stunning views and explore local attractions. Whether you're here for a family vacation, a romantic getaway, or a solo retreat, we strive to make your stay enjoyable and memorable. We look forward to welcoming you!

Show more

Luxury Amenities:

  1. Wake up to breathtaking ocean views, a stunning start to every morning.
  2. Stay right on the oceanfront and let the sound of waves become your personal soundtrack.
  3. Enjoy convenient transportation with our exclusive shuttle services for seamless travel.
  4. Stay productive with top-notch business services available at your fingertips.
Show more

Most booked hotels with Spa in The Keys

luxury hotels in The Keys
81801 Overseas Highway Mile Marker 82, Islamorada, FL 33036, United States of America
8.6
1061 reviews
From $865
luxury hotels in The Keys
1 Knights Key Boulevard MM47, Marathon, FL 33050, United States of America
8.7
637 reviews
From $2572
luxury hotels in The Keys
1401 Simonton Street, Downtown Key West, Key West, FL 33040, United States of America
9.3
634 reviews
From $808

Budget hotels with Spa in The Keys

luxury hotels in The Keys
1500 5th Avenue South, Naples, FL 34102, United States of America
9.6
7 reviews
From $369
luxury hotels in The Keys
1401 Simonton Street, Downtown Key West, Key West, FL 33040, United States of America
9.3
634 reviews
From $808
luxury hotels in The Keys
81801 Overseas Highway Mile Marker 82, Islamorada, FL 33036, United States of America
8.6
1061 reviews
From $865

Compare the Top Luxury Hotels with Spa in The Keys – Addresses, Prices, Stars, Rating, and Review Count

Hotel Name Address Price ($) Star Rating Review Count Book
Cheeca Lodge & Spa 81801 Overseas Highway Mile Marker 82, Islamorada, FL 33036, USA 865 5 8.6 1061
Playa Largo Resort & Spa, Autograph Collection 97450 Overseas Highway, Key Largo, FL 33037, USA 989 5 8.6 344
Isla Bella Beach Resort & Spa - Florida Keys 1 Knights Key Boulevard MM47, Marathon, FL 33050, USA 2572 5 8.7 637
Santa Maria Suites Resort 1401 Simonton Street, Downtown Key West, Key West, FL 33040, USA 808 4 9.3 634
The Gardens Hotel 526 Angela Street, Downtown Key West, Key West, FL 33040, USA 1074 4 9.6 146
Ocean Key Resort & Spa, a Noble House Resort Zero Duval, Downtown Key West, Key West, FL 33040, USA 2138 4 8.4 141
JW Marriott Marco Island Beach Resort 400 South Collier Boulevard, Marco Island, FL 34145, USA 1356 4 8.6 397
Naples Bay Resort and Marina 1500 5th Avenue South, Naples, FL 34102, USA 369 4 9.6 7

Note: The prices for each hotels in The Keys do vary. This can be because of the number of people you are booking for, how far in advance you book and the season. The prices above are only meant as a rough estimate for comparison purposes. Click the buttons above (or click here>) to get the latest prices.

Frequently Asked Questions

Some of the best hotels with spa services in The Keys include the Little Palm Island Resort & Spa, Spa at Hawks Cay Resort, and the Ocean Key Resort & Spa. Each offers a unique blend of luxury and relaxation, making them ideal for unwinding during your stay.

While The Keys doesn’t have many all-inclusive resorts, some like the Bungalows Key Largo offer packages that may include spa services. It’s best to check directly with the resort for specific offerings.

Yes, several beachfront hotels in The Keys feature spa facilities. Notable mentions are the Sunset Key Cottages and the Casa Marina Resort, both providing stunning ocean views alongside their exceptional spa services.

Spas in The Keys typically offer a wide range of treatments including massages, facials, body scrubs, and wellness therapies. Many resorts also provide specialized services using local ingredients to enhance your relaxation experience.

Booking a spa appointment at hotels in The Keys is usually straightforward; you can either call the hotel directly or use their website to make reservations. It's recommended to book in advance, especially during peak tourist seasons.

Absolutely! Resorts like the Hawks Cay Resort cater to families while offering spa services, ensuring both adults and kids can enjoy their vacation time. They often have special packages tailored for family experiences.

When selecting a hotel with a spa in The Keys, consider the variety of treatments offered, the ambiance of the spa, proximity to the beach, and guest reviews. Amenities like pools and dining options are also important for a well-rounded experience.

Many hotels in The Keys allow non-guests to book spa appointments, but it's advisable to check in advance as policies vary by property. This is a great option if you're looking to relax even without an overnight stay.

3-Day The Keys Itinerary If You're Staying at a Luxury Hotel

Day 1:

  • Morning: Start your day with a leisurely breakfast at Breakfast at Tiffany's, known for its delightful menu and beautiful views. Afterward, stroll through the History of Hurricanes Museum to learn about the fascinating maritime history of the Keys.
  • Afternoon: Indulge in a luxurious spa treatment at your hotel or visit the Hemingway House for a glimpse into the life of the famous author. Explore the charming shops and art galleries in the Key West Historic District.
  • Evening: Dine at Morada Bay Beach Cafe, where you can enjoy fresh seafood and picturesque sunsets right on the beach.

Day 2:

  • Morning: Enjoy a private yoga session by the ocean, offered at many luxury hotels. Then, head over to Little White House to explore the historic retreat of President Harry S. Truman.
  • Afternoon: Savor a gourmet lunch at Blue Macaw Island Eatery. Post-lunch, take a scenic drive down the iconic U.S. Route 1, stopping at viewpoints along the way.
  • Evening: Experience the vibrant nightlife at Mallory Square, renowned for its sunset celebrations filled with local artists and performers.

Day 3:

🛏️ Hotels perfect for this itinerary: Ocean Key Resort & Spa, Little Palm Island Resort & Spa, Casa Marina Key West, A Waldorf Astoria Resort

Where to Stay in The Keys: Best Areas by Traveler Type

Choosing the right area to stay in The Keys is essential for tailoring your vacation experience to your specific needs. This picturesque destination boasts diverse neighborhoods, each offering unique atmospheres and amenities. Whether you're seeking romance, family fun, solo adventures, or luxury indulgence, this guide will help you find the perfect fit for your stay in The Keys.

👫 Where to Stay in The Keys for Couples

Best Areas: Key West, Islamorada

Why it’s perfect: Intimate dining options and sunset views create a romantic atmosphere. Secluded beaches and charming streets ideal for leisurely strolls. Variety of water activities, from snorkeling to sailing, perfect for couples.

Top Hotels: The Marker Waterfront Resort, Lands' End Resort, Ocean Key Resort & Spa

Top Features: Romantic views, Charming waterfront, Quiet alleys


👨‍👩‍👧 Where to Stay in The Keys with Family

Best Areas: Duck Key, Marathon

Why it’s perfect: Family-friendly attractions and activities suitable for all ages. Spacious accommodations and amenities tailored for families. Access to beautiful parks and kid-friendly beaches.

Top Hotels: Hawks Cay Resort, Tranquility Bay Beachfront Hotel, Fairfield Inn & Suites by Marriott Marathon

Top Features: Kid-friendly pools, Outdoor adventures, Family-oriented activities


🧳 Where to Stay in The Keys for Solo Travelers

Best Areas: Key Largo, Key West

Why it’s perfect: Vibrant nightlife and social scene for making new friends. Diverse options for excursions, from diving to boat tours. Eclectic shops and cafes perfect for solo exploration.

Top Hotels: Cheeca Lodge & Spa, Ocean Breeze Inn, Tropical Cottages

Top Features: Social atmosphere, Local experiences, Adventure opportunities


👵👴 Where to Stay in The Keys for Seniors

Best Areas: Key West, Marathon

Why it’s perfect: Relaxed pace with easy access to scenic views and cultural sites. Convenient accommodations with accessibility features. Plenty of outdoor spaces for leisurely walks and tours.

Top Hotels: Southernmost Beach Resort, La Te Da Hotel, The Coconut Mallory Resort and Marina

Top Features: Accessibility options, Calm surroundings, Cultural attractions


💸 Where to Stay in The Keys on a Budget

Best Areas: Key Largo, Tavernier

Why it’s perfect: Affordable accommodations without sacrificing quality. Access to beautiful beaches and local eateries at reasonable prices. Opportunities for free or low-cost outdoor activities.

Top Hotels: Holiday Inn Key Largo, Largo Resort, The Pelican Key Largo Cottages

Top Features: Budget-friendly options, Value for money, Local charm


💎 Where to Stay in The Keys for Luxury

Best Areas: Islamorada, Key West

Why it’s perfect: Upscale amenities and exclusive experiences for discerning travelers. Stunning waterfront locations with panoramic views. World-class dining and spa services available on-site.

Top Hotels: Amara Cay Resort, Little Palm Island Resort & Spa, Casa Marina Key West, A Waldorf Astoria Resort

Top Features: Luxury amenities, Private beaches, Gourmet dining


Where to Stay in The Keys - Quick Guide

Traveler Type Best Areas Top Features
Couples Key West, Islamorada Romantic views, Charming waterfront, Quiet alleys
Family Duck Key, Marathon Kid-friendly pools, Outdoor adventures, Family-oriented activities
Solo Key Largo, Key West Social atmosphere, Local experiences, Adventure opportunities
Seniors Key West, Marathon Accessibility options, Calm surroundings, Cultural attractions
Budget Key Largo, Tavernier Budget-friendly options, Value for money, Local charm
Luxury Islamorada, Key West Luxury amenities, Private beaches, Gourmet dining